Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
نویسندگان
چکیده
منابع مشابه
Vascular risk factors and diabetic neuropathy.
BACKGROUND Other than glycemic control, there are no treatments for diabetic neuropathy. Thus, identifying potentially modifiable risk factors for neuropathy is crucial. We studied risk factors for the development of distal symmetric neuropathy in 1172 patients with type 1 diabetes mellitus from 31 centers participating in the European Diabetes (EURODIAB) Prospective Complications Study. METH...
متن کاملPathogenesis of Painful Diabetic Neuropathy
The prevalence of diabetes is rising globally and, as a result, its associated complications are also rising. Painful diabetic neuropathy (PDN) is a well-known complication of diabetes and the most common cause of all neuropathic pain. About one-third of all diabetes patients suffer from PDN. It has a huge effect on a person's daily life, both physically and mentally. Despite huge advances in d...
متن کاملThe Risk Factors in Serum of Peripheral Neuropathy Diabetic and Type 2 Diabetes Patients
Aims: The study's purpose was to evaluate the serious risk factor for the neuropathy disease in patients with diabetes Material & Methods: This research was done on 120 subjects classified into 40 with DPN T2DM and 40 with T2DM and 40 healthy considered as a control. As the conditions of the Iraqi Ministry of Health to evaluate the thesis clinically, that the number of samples examined should ...
متن کاملRelationship of Vascular Factors on Electrophysiologic Severity of Diabetic Neuropathy.
OBJECTIVE To investigate the impact of vascular factors on the electrophysiologic severity of diabetic neuropathy (DPN). METHODS Total 530 patients with type 2 diabetes were enrolled retrospectively. We rated severity of DPN from 1 (normal) to 4 (severe) based on electrophysiologic findings. We collected the data concerning vascular factors (including brachial-ankle pulse wave velocity [PWV],...
متن کاملPathogenesis and prevention of diabetic neuropathy.
Diabetic neuropathy, long-recognized as an important but complex and poorly understood clinical complication of diabetes, is finally yielding to more than a decade of intense clinical and laboratory investigation. At least one basic biochemical mechanism involving sorbitol and MI metabolism, phosphoinositides, protein kinase C, and the (Na,K)-ATPase has been identified that can rationally accou...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2001
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s001250100001